Filling and closing machines 
SFM series
The machines and lines of the SFM series are designed for processing nested containers such as vials, cartridges and disposable syringes. The dosing station is designed to process liquid products using rotary piston pumps. However, it can also be equipped with alternative dosing technology such as peristaltic pumps or a time-pressure dosing system. Depending on machine type and equipment, nests are supplied manually or fully automatically. Filling and closing are always fully automatic. The machines are also designed for vacuum-assisted dosing and insertion of plunger stoppers. This virtually eliminates entrapped air when filling disposable syringes with pharmaceutical product.
HIGHLIGHTS
- High process reliability
- Compact design
- Optimal laminar air flow
- Pharmaceutical design
| Type of machine | Output | Processing range |
|---|---|---|
| SFM5110 |
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| SFM5072 |
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| SFM5105 (VarioSys) |
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Easy and centralized operation
Short set-up time
Low-particle closure feed
Precise maintenance of production parameters
- Barrier systems – RABS and cleanroom isolator
- Alternative dosing systems (e.g. peristaltic pumps, time-pressure dosing system)
- Gas flushing with a controlled amount of gas during filling and closing
- SIP/CIP-compatible dosing components
- Fully automatic In-Process Control (IPC)
- Vacuum-assisted dosing and closing of containers
- Various dosing vessels and supply hoppers
- Service portal vision system (cleanroom compatible)
- A range of checking and alarm devices and counters
- Software upgrades
- Qualification (IQ/OQ)
CIP/SIP
"Cleaning in place – sterilizing in place" is a system for cleaning and/or sterilizing product-carrying parts as installed. Our CIP/SIP system offers a high level of process reliability while saving work and time, as well as cutting cleaning and sterilization costs.All parts which come into contact with the product are rinsed intensively with suitable cleaning media. There is no need to remove any parts. Once the cleaning and sterilization process has been completed, the entire system is cooled and kept under vacuum until the start of production. All applicable technical and pharmaceutical regulations, such as DIN, GMP and FDA, are observed and applied.
Dosing systems
Rotary piston pumpsThe rotary piston pumps comprise only two parts. The dose is defined by the pump stroke setting. They are self-priming and dispense pharmaceutical products very gently and with great precision.
Single-hose peristaltic pumps
Only one product hose is required from the product vessel to the dosing needle. The single-hose peristaltic pumps do not require a Y-manifold, which means that the dosing system itself is very straightforward and easy to use.
Time/pressure dosing system
Product is supplied from a dosing vessel equipped with a precision pressure controller. Only one product hose is required from the pressure controller to the dosing needle. This electronically controlled dosing process allows production data to be acquired and documented.
Barrier systems – RABS
Aseptic ambient conditions free of contamination can be created using RABS (Restricted Access Barrier Systems).
- Passive RABS
- Active RABS
- Closed RABS
- Isolator
Taking the building and room situation into account, these systems provide optimum air flow conditions.
smartline
Are you looking for an approved off the shelf machine concept with short delivery times, but still want to be able to optimize your line to suit your specific needs?By choosing our smartline concept you can select your personal solution from pre-engineered options and still maintain your flexibility. smartline guarantees a more efficient project workflow. Maintenance, qualification and spare parts procurement are not only faster, but also easier to handle over the entire life cycle of the line. Eliminate time-consuming engineering phases and benefit from reliable solutions that come ready to use straight out of the box.
